You get this error when running your application:
Sys.WebForms.PageRequestManagerParserErrorException: The message received from the server could not be parsed.

When authentication is turned on, a session time out will cause a Sys.WebForms.PageRequestManagerParserErrorException when a post back occurs on a control with smooth panels turned on. Response.write is not compatible with updatepanel which causes this error.
See:
http://weblogs.asp.net/leftslipper/archive/2007/02/26/sys-webforms-pagerequestmanagerparsererrorexception-what-it-is-and-how-to-avoid-it.aspx
Override the RedirectToLoginPage method in:
…\app_code\shared\BaseApplicationPage.cs or .vb
Visual Basic .NET:
Public Overrides Sub RedirectToLoginPage()
Dim loginUrl As String = BaseClasses.Configuration.ApplicationSettings.Current.SignInPageUrl()
If (NetUtils.IsEqual(Me.Request, loginUrl)) Then
Return
End If
Me.SystemUtils.shouldRollBackTransaction = True
Me.SystemUtils.shouldDisplayTransactionError = False
Me.Response.ClearContent()
Me.SetResponseUncacheable()
Me.Response.Redirect(loginUrl)
'NetUtils.RedirectClientLocation(loginUrl, Me.Response, True)
End Sub
Part VII: Troubleshooting Applications
Application Runs But No Data is Displayed